Watching your dog have a seizure is scary—there’s no way around it. Whether your pup has been diagnosed with epilepsy or experiences seizures due to toxicity, inflammation, or an underlying health condition, it’s something no pet parent wants to go through. While conventional medications like phenobarbital and potassium bromide are often prescribed, many dog owners are looking for natural ways to support their dog’s brain health, reduce seizure frequency, and improve overall neurological stability.
So, let’s dive into some of the best natural supplements for seizure support in dogs, how they work, and what science says about their effectiveness. We’ll also touch on some holistic strategies—because taking a big-picture approach can make a world of difference.
What Causes Seizures in Dogs?
Before we get into the supplements, let’s talk about why seizures happen in the first place. A seizure is essentially a misfire in the brain—an abnormal burst of electrical activity that leads to uncontrollable shaking, twitching, or even loss of consciousness. But what’s behind it? Some of the most common causes include:
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Idiopathic epilepsy – The most common cause, often genetic with no identifiable underlying condition.
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Nutritional deficiencies – Low levels of magnesium, taurine, or B vitamins can contribute to neurological dysfunction.
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Toxins and heavy metals – Exposure to pesticides, processed foods, or household chemicals can overload your dog's system.
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Liver or kidney disease – If your dog’s body isn’t properly detoxifying, toxins can build up and trigger seizures.
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Inflammation and oxidative stress – Chronic inflammation in the brain can create the perfect storm for seizures.
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Gut health imbalances – There’s a strong connection between the gut and brain, and an unhealthy gut can make neurological issues worse.
A holistic approach—including diet, lifestyle, and supplements—can help address some of these underlying triggers and improve your dog’s quality of life.
Top Natural Approaches for Seizure Support in Dogs
Keto Diet – A Game-Changer for Seizure Control
The ketogenic diet isn’t just a human health trend—it’s been extensively studied for its role in reducing seizures in both people and animals. This high-fat, moderate-protein, low-carb diet shifts the body from using glucose for energy to producing ketones, which are a more stable and efficient fuel source for the brain.
Why keto works for seizures:
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Keeps blood sugar levels stable, preventing spikes that can trigger seizures.
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Increases ketone production, which supports brain health.
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Lowers inflammation and oxidative stress, helping to calm overactive neurons.
For dogs, this means incorporating healthy fats like grass-fed meats, wild-caught fish, and eggs while cutting out processed carbs and starchy foods. If switching to full keto isn’t an option, even lowering carb intake and increasing healthy fats can be beneficial.
MCT Oil – Quick Brain Fuel with Seizure-Fighting Benefits
MCT (medium-chain triglyceride) oil is a powerhouse supplement for brain health. It helps the body produce ketones quickly, without requiring strict dietary ketosis, making it an easy way to give your pup the brain-boosting benefits of a ketogenic diet without a complete diet overhaul.
Why MCT oil is great for dogs with seizures:
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Provides an immediate source of brain-friendly energy.
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Supports mitochondrial function (which is key for reducing seizures).
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Has anti-inflammatory properties that help calm the nervous system.
Look for a high-quality, organic MCT oil and introduce it slowly to avoid digestive upset.
High-Dose Omega-3 Fatty Acids – Brain Food at Its Best
Omega-3s, particularly EPA and DHA from fish oil, are essential for brain health and can help reduce seizure frequency by lowering neuroinflammation and improving communication between brain cells.
How omega-3s help with seizures:
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Reduce inflammation that can contribute to seizure activity.
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Support cognitive function and brain cell repair.
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Help balance neurotransmitters for more stable brain activity.
For best results, go for a high-quality fish oil or algae-based omega-3 supplement, making sure it’s free from heavy metals and contaminants.
Magnesium – The Ultimate Calming Mineral
Magnesium is often overlooked, but it’s one of the most important minerals for nerve function and muscle relaxation. If your dog is deficient, their neurons can become overexcited—leading to a higher risk of seizures.
Why magnesium is essential:
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Helps regulate electrical activity in the brain.
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Supports nerve function and muscle relaxation.
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Reduces stress and anxiety, which can be seizure triggers.
Magnesium glycinate or magnesium threonate are the most bioavailable forms, meaning they’re easy for your dog’s body to absorb.
B Vitamins – Especially B6 for Neurological Health
B vitamins, particularly B6, play a huge role in brain health. B6 is necessary for producing GABA, a calming neurotransmitter that helps prevent overactivity in the brain. Deficiency in B6 has been linked to increased seizure activity.
Why B vitamins matter:
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Support neurotransmitter function.
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Reduce brain inflammation and oxidative stress.
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Help prevent seizure triggers related to nutritional deficiencies.
A high-quality methylated B-complex supplement designed for dogs can ensure they’re getting enough.
CBD Oil – One of the Best Natural Seizure Support Remedies
CBD (cannabidiol) has gained a ton of attention for its potential in reducing seizures—and for good reason. Studies have shown that CBD can help regulate neurotransmitter activity and calm overactive neurons.
What makes CBD great for dogs with seizures:
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Helps relax the nervous system and reduce overactivity in the brain.
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Decreases seizure frequency and severity.
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Provides anti-inflammatory and antioxidant support.
Go for a high-quality, full-spectrum CBD oil with no additives or fillers, and start with a low dose to gauge your dog’s response.
Final Thoughts
Managing seizures naturally isn’t about just one magic supplement—it’s about taking a whole-body approach. A combination of dietary changes, toxin reduction, and natural supplements like MCT oil, omega-3s, magnesium, B vitamins, and CBD can provide incredible support for your pup’s brain health.
It’s always best to work with a holistic vet to customize a plan that fits your dog’s specific needs. Every dog is unique, and what works for one may not work for another. But with the right approach, you can help your dog live a happier, healthier life with fewer seizures.